21C Museum Hotel Louisville | Louisville ★ Book Spa Rooms, Wellness Deals & Guest Reviews

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About the Hotel

700 West Main Street, Louisville, Kentucky, United States, 40202

“The hotel's location made exploring Louisville's attractions effortless and enjoyable.”view full review

21C Museum Hotel Louisville offers a unique blend of contemporary art and boutique accommodations. This 5-star hotel features 91 guest rooms, an on-site restaurant called Proof on Main, and over 9000 square feet of exhibition space. Guests can enjoy amenities such as free WiFi and a dedicated event staff.

Rooms & Amenities

The guest rooms at 21C Museum Hotel Louisville are designed with both comfort and artistic expression in mind. Each room includes a premium Bryte Restorative Sleep Bed, a flat-screen TV, and a mini-bar. Many rooms feature unique artworks and multi-purpose furniture designed by artists.

Dining & Events

Dining options include Proof on Main, which showcases Southern and Appalachian-inspired cuisine. The restaurant also hosts exclusive events such as the Fork & Bottle dinner series featuring regional spirits. Additionally, catering services are available for events held at the hotel.

Leisure & Attractions

Leisure facilities at 21C Museum Hotel include a fitness center and access to curated exhibitions in the hotel's galleries. Guests can explore nearby attractions such as the Louisville Slugger Museum & Bat Factory and the Muhammad Ali Center, located within a half mile. Events and performances often take place in association with the gallery exhibitions.

Business & Services

For business and events, 21C Museum Hotel offers four private galleries for meetings accommodating 10 to 60 guests. A dedicated event staff is available to assist with planning. Public transportation options include bus routes accessible within walking distance from the hotel.

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Choose your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals

Room Balcony

2 persons

29 m²

1 King-size bed

Shower

Coffee machine

room details

Deluxe King Room

2 persons

31 m²

1 King-size bed

Shower

Coffee machine

room details

Corner Suite

2 persons

61 m²

1 King-size bed

Shower

Coffee machine

room details

Deluxe King Suite

2 persons

46 m²

1 King-size bed

Shower

Coffee machine

room details

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Price and Room Availability

Check availability and prices for your dates now!

Getting around

Comprehensive guide to transport options for seamless travel

City Centre

Louisville 1.9 km

Airports

Louisville (SDF) 11.9 km

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

Delicious Brunch Experience

“I had the chance to dine at Proof for Saturday brunch during my stay at 21C. The food options were fantastic, and the atmosphere was vibrant, making it such a pleasant way to start the day. The server even made custom accommodations to the menu for me, which I truly appreciated. I highly recommend dining here!” view full review

Unique and Inviting Rooms

“Staying in the Cyclone Room was an absolute delight! The room was not only spacious and well-appointed, but the special black-lit bathroom added a unique touch, made the experience feel like sleeping in a gallery. The bedding was luxurious and the body products provided were great. I loved every minute of it!” view full review

Art-Packed Environment

“One of the standout features of my stay was the engaging art installations throughout the hotel. Walking around seemed like an art museum visit, with unique pieces displayed everywhere I looked. The convenience of having such very nice art at my fingertips made my entire experience feel rich and creative.” view full review

Relaxing Steam and Sauna

“During my visit, I took full advantage of the steam and sauna facilities. It was a calming retreat after a long day of exploring. Being located just steps away from my room made it easy, and it truly enhanced my relaxation experience at 21C. I can't wait to return for another rejuvenating stay!” view full review

General

No smoking on site
Free Wi-Fi
Parking
Safe deposit box
24-hour reception
Pets allowed
Rooms/ Facilities for disabled
Wheelchair access
Security
Luggage storage
Locker room
Allergy-free rooms
Lift
ATM/Cash machine
Smoke detectors
Electric vehicle charging station
Fire extinguishers

Sports & Fitness

Fitness centre
Yoga class

Guest Parking

Cookware/ Kitchen utensils

Services

Valet parking
Room service
Housekeeping
Laundry
Dry cleaning
Welcome drink

Dining

Restaurant
Bar/ Lounge area
Outdoor dining area

Business

Business centre
Meeting/ Banquet facilities
Fax/Photocopying

Children

Cots

Spa & Leisure

Spa & wellness centre
Sauna
Turkish bath
Steam room
Full body massage

Room features

Air conditioning
Heating
Mini-bar
Soundproofed rooms
Patio
Tea and coffee facilities
Ironing facilities

Bathroom

Free toiletries

Self-catering

Cookware/ Kitchen utensils

Media

Flat-screen TV

Room decor

Carpeted floor

Location

700 West Main Street, Louisville, Kentucky, United States, 40202

Map view

700 West Main Street, Louisville, Kentucky, United States, 40202

City landmarks

Square

Fourth Street Live

800 m

Stadium

Louisville Slugger Field

1.7 km

Event hall

Kentucky International Convention Center

900 m

Landmark

KFC Yum Center

680 m

Park

Waterfront Park

1.3 km

Church

Cathedral of the Assumption

630 m

Landmark

Freedom Hall

1.1 km

Museum

Thomas Edison House

2.0 km

Landmark

Angel's Envy Distillery

1.6 km

Landmark

Jim Beam Urban Stillhouse

860 m

Bridge

Big Four Bridge

2.2 km

Library

Louisville Free Public Library

1.4 km

Bridge

The Big Four Bridge

2.2 km

Landmark

Old Forester Distilling

1.2 km

Landmark

West Main Historic District

2.3 km

Museum

African American Heritage House Museum

2.1 km

Park

Falls of the Ohio State Park

4.1 km

Nearby

Museum

Louisville Slugger Museum & Bat Factory

180 m

Museum

Muhammad Ali Center

280 m

Museum

Kentucky Science Center

140 m

Museum

The Frazier History Museum

260 m

Museum

Kentucky Museum of Art and Craft

70 m

528 W Main St

Evan Williams Bourbon Experience

200 m

Gallery

Flame Run Glass Studio and Gallery

300 m

500 W Main St

The Belvedere

250 m

Night club

Jimmy Can't Dance

90 m

801 W Main St

Michter's Fort Nelson Distillery

150 m

Library

Sons of the American Revolution Genealogical Research Library

190 m

120 N 10th St

Kentucky Peerless Distilling Co

480 m

401 W River Rd

Belle of Louisville Riverboats

580 m

Restaurants

Proof On Main

10 m

702 West Main Street

Mussel & Burger Bar Downtown

60 m

113 S 7th St Located in Louisville's Central Business District

Bristol Bar & Grille

110 m

614 W Main St

Atlantic No. 5

160 m

605 W Main St Located in Louisville's Central Business District.

Los Aztecas Mexican Restaurant

180 m

445 E Market St

Vincenzo's Italian Restaurant

430 m

150 S 5th St

Jockey Silks Bourbon Bar

480 m

140 N 4th St 2nd Floor - West Tower

Dish on Market

470 m

434 W Market St

Quiznos

540 m

223 S 5th St

Swizzle Dinner & Drinks

530 m

140 N Fourth St 25th Floor

Cafe Magnolia

590 m

140 N 4th St Galt House Hotel

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21C Museum Hotel Louisville, Louisville

About the Hotel

Rooms & Amenities

Dining & Events

Leisure & Attractions

Business & Services

Choose your room type

Price and Room Availability

Getting around

Facilities

General

Sports & Fitness

Guest Parking

Services

Dining

Business

Children

Spa & Leisure

Room features

Bathroom

Self-catering

Media

Room decor

Location

Next best alternative

Inspiration for future getaways